Hydrogen bonding between "side chains" occurs in
a variety of circumstances. The most usual cases are between
two alcohols, an alcohol and an acid, two acids, or an alcohol
and an amine or amide. In giving the structures for various examples,
the backbone of the protein fragment will be represented by a
short helix with only the side chain structure given as in the
graphic on the left.
In the prion protein, tyr 128 is hydrogen bonded to asp 178,
which cause one part of the chain to be bonding with a part some
Prion Protein - Chime
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Examples of amino acid side chains that may hydrogen bond
to each other:
Two alcohols: ser, thr, and tyr.
Alcohol and an acid: asp and tyr
Two acids: asp and glu
Alcohol and amine: ser and lys
Alcohol and amide: ser and asn
|Quiz:Name other amino acids
that may engage in hydrogen bonding. Other answers are possible
Alcohol and Acid?
|Alcohol and Amine?
| Alcohol and Amide?