Reaction 4: Oxidation
This is the first oxidation reaction in which an alcohol is
converted to a ketone. Two hydrogens and 2 electrons are transferred
to NAD+ to NADH + H+. This is the entry
point into the electron transport chain.
The product of this reaction, oxalosuccinate remains attached
to the isocitrate dehydrogenase for the next step.
This reaction is catalyzed by isocitrate dehydrogenase.
This reaction is catalyzed by aconitase.