Isocitric Acid

 

Reaction 4: Oxidation

This is the first oxidation reaction in which an alcohol is converted to a ketone. Two hydrogens and 2 electrons are transferred to NAD+ to NADH + H+. This is the entry point into the electron transport chain.

The product of this reaction, oxalosuccinate remains attached to the isocitrate dehydrogenase for the next step.

This reaction is catalyzed by isocitrate dehydrogenase.

This reaction is catalyzed by aconitase.

Oxalosuccinic Acid 

Color Codes
C

H

N

O

P

S

Cl

F

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Oxidize -OH to a ketone
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