Dr. Stacey Raimondi studies the molecular mechanisms of cancer metastasis, specifically focusing on changes in gene and protein expression between normal and cancer cells, with the hopes of developing novel therapeutics in the treatment of cancer. Her work with Elmhurst students has examined the role of an aberrant DNA methyltransferase 3B7 (DNMT3B7) in promoting tumor progression. While their initial studies began in breast cancer, they have now expanded to study virtually every tumor type with available data utilizing molecular and cellular techniques as well as bioinformatics.
Dr. Raimondi earned a Ph.D. in Anatomy and Cell Biology from the University of Iowa. Her doctoral project examined the role of lysyl oxidase in breast cancer cell motility.
- BIO 100 Principles of Biology
- BID 106 Forensics
- BIO 200 General Biology I
- BIO 341 Immunology
- BIO 342 Molecular and Cellular Biology of Cancer
- BIO 443 Advanced Cell Physiology
- Siddiqui, S.*, S. Chaudhry*, T.K. Steffen*, S.L. Raimondi. 2017. Blackseed (Nigella sativa) oil and its active ingredient, thymoquinone, suppress the aggressive phenotype of breast cancer cells. Am. J. Undergrad. Res. 14(2): 5-12.
- Raimondi, S.L. 2016. ImmuneQuest: Assessment of a video game as a supplement to an undergraduate immunology course. J. Microbio. Bio. Educ. 17(2): 237-245.
- Mullin, C.C.S.*, J.J. Busser*, A.M. Ciampanelli*, S.L. Raimondi. 2016. Aberrant DNMT3B7 expression correlates to age, race, and hormone receptor status in breast cancer patients. Am. J. Undergrad. Res. 13(1): 11-19.
- Hameed, R.*, S.L. Raimondi. 2015. The role of aberrant DNMT3Bs in tumor progression – a review. Cancer Cell Microenviron. 2(2): e847.
- Marsh, T.L., M.F. Guenther, S.L. Raimondi. 2015. When do students “learn to comprehend” scientific sources?: Evaluation of a critical skill in learning to write and writing to learn outcomes. J. Microbio. Bio. Educ. 16(1):13-20.
- Brambert, P.R.*, D.J. Kelpsch*, R. Hameed*, C.V. Desai*, G. Calafiore*, L.A. Godley, S.L. Raimondi. 2015. DNMT3B7 promotes tumor progression to a more aggressive phenotype in breast cancer cells. PLoS ONE. 10(1): e0117310.
- Raimondi, S.L., T.L. Marsh, P.E. Arriola. Integrating Vision and Change into a Biology Curriculum at a Small Comprehensive College. J. College Sci. Teach. 43(5):33-37.
- Raimondi, S.L. Development of a Bi-Disciplinary Course in Forensic Science. J. Microbio. Bio. Educ. 14(2):250-251.
- Ostler, K.R., Q. Yang, T. J. Looney, L. Zhang, A. Vasanthakumar, Y. Tian, M. Kocherginsky, S.L. Raimondi, J.G. DeMaio*, H.R. Salwen, S. Gu, A. Chlenski, A. Naranjo, A. Gill, R. Peddinti, B.T. Lahn, S.L. Cohn, L.A. Godley. 2012. DNMT3B7, a truncated DNMT3B isoform, suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. Cancer Research. 72(18):4714-4723.
- Kelpsch, D.J.*, L.E. Williams*, A. Du*, C.L. Hulstein*, M.K. Advani*, S.L. Raimondi. 2012. A comparison of the E-cadherin-regulated Ras/MAP kinase pathway in two breast cancer cell lines. BIOS. 83(1):17-25.
- Williams, L.E.*, A. Du*, D.J. Kelpsch*, C.L. Hulstein*, M.K. Advani*, S.L. Raimondi. 2011. The role of DNMT3B7 and ∆DNMT3B6 in metastasis of breast cancer cells. Proceedings of the National Conference on Undergraduate Research. 1977-1983.
- Postovit, L-M., D.E. Abbott, S.L. Payne, W.W. Wheaton, N.V. Margaryan, R. Sullivan, M.K. Jansen, K. Csiszar, M.J.C. Hendrix, D.A. Kirschmann. 2008. Hypoxia/reoxygenation – A dynamic regulator of lysyl oxidase-facilitated breast cancer migration. J. Cell Biochem. 103(5):1369-1378.
- Ostler, K.R., E.M. Davis, S.L. Payne, B.B. Patel, J. Expósito-Céspedes, M.M. LeBeau, L.A. Godley. 2007. Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene. 26(38):5553-5563.
- Payne, S.L.,J.C. Hendrix, and D.A. Kirschmann. 2007. Paradoxical roles for lysyl oxidases in cancer – A prospect. J. Cell Biochem. 101(6):1338-1354.
- Payne, S.L., J.C. Hendrix, and D.A. Kirschmann. 2005 Lysyl oxidase regulates actin filament formation through the p130Cas/Crk/DOCK180 signaling complex. J. Cell Biochem. 98(4):827-837.
- Payne, S.L., Fogelgren, A.R. Hess, E.A. Seftor, E.L. Wiley, S.F.T. Fong, K. Csiszar, M.J.C. Hendrix, and D.A. Kirschmann. 2005. Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. Cancer Research. 65(24): 11429-11436.